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Research Molecular Properties of Heterocyclic Compounds Heterocyclic compounds with the SO2 moiety J. Chem. Soc., Perkin Trans II, 1996, 293-297.
Research Molecular Properties of Heterocyclic Compounds Heterocyclic compounds with the SO2 moiety J. Chem. Soc., Perkin Trans II, 1996, 293-297.J. Chem. Soc., Perkin Trans II, 1996, 293-297.
Synthesis, hydrolysis reactions and conformational study of 2-substituted 3,5-diamino-4-nitroso-2H-1,2,6-thiadiazine 1,1-dioxides
The 2-substituted 3,5-diamino-4-nitroso-2H-1,2,6-thiadiazine 1,1-dioxides are present in solution as a mixture of two rotational conformers of the nitroso group that are stabilized by hydrogen bonds with the amino groups in positions 3 and 5. The stability of these conformations has been studied using 1H, 13C and 15N NMR spectroscopy, as well as molecular orbital ab initio calculations. In addition, hydrolysis reactions of these compounds have been carried out affording 5-amino-4-hydroxyimino-3-oxo-3,4-dihydro-2H-1,2,6-thiadiazine 1,1-dioxides and 4-amino-3-oxo-2,3-dihydro-1,2,5-thiadiazole 1,1-dioxides.